Microwave-assisted Synthesis and antifungal activity of coumarin[8,7-e][1,3]oxazine derivatives.
Mol Divers
; 20(3): 611-8, 2016 Aug.
Article
en En
| MEDLINE
| ID: mdl-26880591
ABSTRACT
The synthesis of novel coumarin[8,7-e][1,3]oxazine derivatives through a microwave-assisted three-component one-pot Mannich reaction is described in this study. All the target compounds were evaluated in vitro for their antifungal activity against Botrytis cinerea, Colletotrichum capsici, Alternaria solani, Gibberella zeae, Rhizoctonia solani, and Alternaria mali. The preliminary bioassays showed that 5e, 5m, and 5s exhibited good antifungal activity and the most active compound was 5m with an [Formula see text] value as low as 2.1 nM against Botrytis cinerea.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Oxazinas
/
Cumarinas
/
Antifúngicos
Idioma:
En
Revista:
Mol Divers
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2016
Tipo del documento:
Article