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Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Stritt, Simon; Nurden, Paquita; Favier, Remi; Favier, Marie; Ferioli, Silvia; Gotru, Sanjeev K; van Eeuwijk, Judith M M; Schulze, Harald; Nurden, Alan T; Lambert, Michele P; Turro, Ernest; Burger-Stritt, Stephanie; Matsushita, Masayuki; Mittermeier, Lorenz; Ballerini, Paola; Zierler, Susanna; Laffan, Michael A; Chubanov, Vladimir; Gudermann, Thomas; Nieswandt, Bernhard; Braun, Attila.
Afiliación
  • Stritt S; Chair of Experimental Biomedicine, University Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Nurden P; Rudolf Virchow Centre, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Favier R; Chair of Experimental Biomedicine, University Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Favier M; Institut Hospitalo-Universitaire LIRYC, Plateforme Technologique d'Innovation Biomédicale, Hôpital Xavier Arnozan, Avenue du Haut Lévêque, 33604 Pessac, France.
  • Ferioli S; Assistance Publique-Hôpitaux de Paris, Haematological Laboratory, Armand Trousseau Children Hospital, 26 Avenue du Docteur Arnold-Netter, 75012 Paris, France.
  • Gotru SK; Inserm U1170, Gustave Roussy, University Paris Sud, 114 Rue Edouard Vaillant, 94805 Villejuif, France.
  • van Eeuwijk JM; Inserm U1170, Gustave Roussy, University Paris Sud, 114 Rue Edouard Vaillant, 94805 Villejuif, France.
  • Schulze H; Inra, UMR_INRA 1260, 27 Boulevard Jean Moulin, 13385 Marseille, France.
  • Nurden AT; Aix Marseille Université, 58 Boulevard Charles Livon, 13284 Marseille, France.
  • Lambert MP; Inserm UMR_S 1062, 27 Boulevard Jean Moulin, 13385 Marseille, France.
  • Turro E; Walther-Straub-Institute for Pharmacology and Toxicology, Ludwig-Maximilians University Munich, Goethestraße 33, 80336 Munich, Germany.
  • Burger-Stritt S; Chair of Experimental Biomedicine, University Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Matsushita M; Rudolf Virchow Centre, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Mittermeier L; Chair of Experimental Biomedicine, University Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Ballerini P; Rudolf Virchow Centre, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Zierler S; Chair of Experimental Biomedicine, University Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97078 Würzburg, Germany.
  • Laffan MA; Institut Hospitalo-Universitaire LIRYC, Plateforme Technologique d'Innovation Biomédicale, Hôpital Xavier Arnozan, Avenue du Haut Lévêque, 33604 Pessac, France.
  • Chubanov V; Division of Haematology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, Pennsylvania 19104, USA.
  • Gudermann T; Department of Paediatrics, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, Pennsylvania 19104, USA.
  • Nieswandt B; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Francis Crick Ave, Cambridge CB2 0S, UK.
  • Braun A; NHS Blood and Transplant, Cambridge Biomedical Campus, Francis Crick Ave, Cambridge CB2 0S, UK.
Nat Commun ; 7: 11097, 2016 Mar 29.
Article en En | MEDLINE | ID: mdl-27020697
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citoesqueleto / Proteínas Serina-Treonina Quinasas / Trombopoyesis / Canales Catiónicos TRPM / Homeostasis / Magnesio Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citoesqueleto / Proteínas Serina-Treonina Quinasas / Trombopoyesis / Canales Catiónicos TRPM / Homeostasis / Magnesio Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania