Syringaresinol induces mitochondrial biogenesis through activation of PPARß pathway in skeletal muscle cells.

Thach, Trung Thanh; Lee, Chan-Kyu; Park, Hyun Woo; Lee, Sang-Jun; Lee, Sung-Joon

Thach, Trung Thanh; Lee, Chan-Kyu; Park, Hyun Woo; Lee, Sang-Jun; Lee, Sung-Joon.

Afiliación

Thach TT; Department of Biotechnology, BK21 Plus Program, Graduate School of Life Sciences and Biotechnology, Department of Food Bioscience and Technology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Lee CK; Department of Biotechnology, BK21 Plus Program, Graduate School of Life Sciences and Biotechnology, Department of Food Bioscience and Technology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Park HW; Department of Biotechnology, BK21 Plus Program, Graduate School of Life Sciences and Biotechnology, Department of Food Bioscience and Technology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Lee SJ; HOLISTICBIO, Pangyoyeok-ro, Bundang-gu, Gyeonggi-do, Republic of Korea; Dongguk University Research Institute of Biotechnology and Medical Converged Science, Goyang-si, Gyeonggi-do, Republic of Korea.
Lee SJ; Department of Biotechnology, BK21 Plus Program, Graduate School of Life Sciences and Biotechnology, Department of Food Bioscience and Technology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Republic of Korea. Electronic address: junelee@korea.ac.kr.

Bioorg Med Chem Lett ; 26(16): 3978-83, 2016 08 15.

Article en En | MEDLINE | ID: mdl-27450788

Asunto(s)

Furanos/química; Lignanos/química; Mitocondrias/efectos de los fármacos; PPAR-beta/metabolismo; Animales; Carnitina O-Palmitoiltransferasa/genética; Carnitina O-Palmitoiltransferasa/metabolismo; Línea Celular; Furanos/aislamiento & purificación; Furanos/farmacología; Expresión Génica/efectos de los fármacos; Lignanos/aislamiento & purificación; Lignanos/farmacología; Ratones; Mitocondrias/metabolismo; Mioblastos/citología; Mioblastos/metabolismo; PPAR-beta/antagonistas & inhibidores; PPAR-beta/genética; Panax/química; Panax/metabolismo; Interferencia de ARN; ARN Mensajero/metabolismo; ARN Interferente Pequeño/metabolismo; Proteína Desacopladora 2/genética; Proteína Desacopladora 2/metabolismo

Palabras clave

Mitochondrial biogenesis; PPARß; Skeletal muscle; Syringaresinol

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lignanos / PPAR-beta / Furanos / Mitocondrias Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google