Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-&#945;-TNFR1-NF-&#954;B pathway and a possible involvement of angiopoietin-like 4 in lung metastasis.

Tanaka, Takuya; Imamura, Takahisa; Yoneda, Masakazu; Irie, Atsushi; Ogi, Hidenao; Nagata, Masashi; Yoshida, Ryoji; Fukuma, Daiki; Kawahara, Kenta; Shinohara, Masanori; Nakayama, Hideki

Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-α-TNFR1-NF-κB pathway and a possible involvement of angiopoietin-like 4 in lung metastasis.

Tanaka, Takuya; Imamura, Takahisa; Yoneda, Masakazu; Irie, Atsushi; Ogi, Hidenao; Nagata, Masashi; Yoshida, Ryoji; Fukuma, Daiki; Kawahara, Kenta; Shinohara, Masanori; Nakayama, Hideki.

Afiliación

Tanaka T; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Imamura T; Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Yoneda M; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Irie A; Department of Immunogenetics, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Ogi H; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Nagata M; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Yoshida R; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Fukuma D; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Kawahara K; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Shinohara M; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Nakayama H; Department of Oral and Maxillofacial Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.

Int J Oncol ; 49(4): 1377-84, 2016 Oct.

Article en En | MEDLINE | ID: mdl-27511626

Asunto(s)

Angiopoyetinas/metabolismo; Carcinoma de Células Escamosas/metabolismo; Neoplasias Pulmonares/metabolismo; Metaloproteinasas de la Matriz Secretadas/metabolismo; Receptores Tipo I de Factores de Necrosis Tumoral/genética; Neoplasias de la Lengua/metabolismo; Factor de Necrosis Tumoral alfa/genética; Proteína 1 Similar a la Angiopoyetina; Proteínas Similares a la Angiopoyetina; Animales; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/patología; Línea Celular Tumoral; Regulación Neoplásica de la Expresión Génica; Humanos; Metástasis Linfática; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones; Ratones Desnudos; FN-kappa B/metabolismo; Invasividad Neoplásica; Trasplante de Neoplasias; Transducción de Señal; Neoplasias de la Lengua/genética; Neoplasias de la Lengua/patología; Factor de Necrosis Tumoral alfa/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Lengua / Carcinoma de Células Escamosas / Factor de Necrosis Tumoral alfa / Angiopoyetinas / Receptores Tipo I de Factores de Necrosis Tumoral / Metaloproteinasas de la Matriz Secretadas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Japón

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