Suppression of NF-&#954;B activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.

Yan, Huimin; Duan, Xin; Pan, Hua; Holguin, Nilsson; Rai, Muhammad Farooq; Akk, Antonina; Springer, Luke E; Wickline, Samuel A; Sandell, Linda J; Pham, Christine T N

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.

Yan, Huimin; Duan, Xin; Pan, Hua; Holguin, Nilsson; Rai, Muhammad Farooq; Akk, Antonina; Springer, Luke E; Wickline, Samuel A; Sandell, Linda J; Pham, Christine T N.

Afiliación

Yan H; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Duan X; Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110.
Pan H; Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Holguin N; Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110.
Rai MF; Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110.
Akk A; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Springer LE; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Wickline SA; Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110 wicklines@aol.com sandelll@wudosis.wustl.edu cpham@wustl.edu.
Sandell LJ; Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110; wicklines@aol.com sandelll@wudosis.wustl.edu cpham@wustl.edu.
Pham CT; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110; wicklines@aol.com sandelll@wudosis.wustl.edu cpham@wustl.edu.

Proc Natl Acad Sci U S A ; 113(41): E6199-E6208, 2016 10 11.

Article en En | MEDLINE | ID: mdl-27681622

Palabras clave

NF-κB; autophagy; nanomedicine; posttraumatic osteoarthritis; siRNA

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article