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Design, synthesis, and evaluation of (2S,4R)-Ketoconazole sulfonamide analogs as potential treatments for Metabolic Syndrome.
Blass, Benjamin E; Iyer, Pravin; Abou-Gharbia, Magid; Childers, Wayne E; Gordon, John C; Ramanjulu, Mercy; Morton, George; Arumugam, Premkumar; Boruwa, Joshodeep; Ellingboe, John; Mitra, Sayan; Nimmareddy, Rajashekar Reddy; Paliwal, Shalini; Rajasekhar, Jamallamudi; Shivakumar, Savithiri; Srivastava, Pratima; Tangirala, Raghuram S; Venkataramanaiah, Konda; Yanamandra, Mahesh.
Afiliación
  • Blass BE; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA. Electronic address: Benjamin.Blass@Temple.edu.
  • Iyer P; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Abou-Gharbia M; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.
  • Childers WE; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.
  • Gordon JC; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.
  • Ramanjulu M; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.
  • Morton G; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA.
  • Arumugam P; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Boruwa J; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Ellingboe J; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Mitra S; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Nimmareddy RR; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Paliwal S; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Rajasekhar J; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Shivakumar S; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Srivastava P; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Tangirala RS; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Venkataramanaiah K; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
  • Yanamandra M; GVK Biosciences Private Limited, Plot 28A, IDA Nacharam, Hyderabad 500076, India.
Bioorg Med Chem Lett ; 26(23): 5825-5829, 2016 12 01.
Article en En | MEDLINE | ID: mdl-27789139
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Síndrome Metabólico / Inhibidores Enzimáticos del Citocromo P-450 / Cetoconazol Límite: Animals / Female / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Síndrome Metabólico / Inhibidores Enzimáticos del Citocromo P-450 / Cetoconazol Límite: Animals / Female / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article