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Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.
Durek, Pawel; Nordström, Karl; Gasparoni, Gilles; Salhab, Abdulrahman; Kressler, Christopher; de Almeida, Melanie; Bassler, Kevin; Ulas, Thomas; Schmidt, Florian; Xiong, Jieyi; Glazar, Petar; Klironomos, Filippos; Sinha, Anupam; Kinkley, Sarah; Yang, Xinyi; Arrigoni, Laura; Amirabad, Azim Dehghani; Ardakani, Fatemeh Behjati; Feuerbach, Lars; Gorka, Oliver; Ebert, Peter; Müller, Fabian; Li, Na; Frischbutter, Stefan; Schlickeiser, Stephan; Cendon, Carla; Fröhler, Sebastian; Felder, Bärbel; Gasparoni, Nina; Imbusch, Charles D; Hutter, Barbara; Zipprich, Gideon; Tauchmann, Yvonne; Reinke, Simon; Wassilew, Georgi; Hoffmann, Ute; Richter, Andreas S; Sieverling, Lina; Chang, Hyun-Dong; Syrbe, Uta; Kalus, Ulrich; Eils, Jürgen; Brors, Benedikt; Manke, Thomas; Ruland, Jürgen; Lengauer, Thomas; Rajewsky, Nikolaus; Chen, Wei; Dong, Jun; Sawitzki, Birgit.
Afiliación
  • Durek P; Experimental Rheumatology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Nordström K; Department of Genetics, University of Saarland, 66123 Saarbrücken, Germany.
  • Gasparoni G; Department of Genetics, University of Saarland, 66123 Saarbrücken, Germany.
  • Salhab A; Department of Genetics, University of Saarland, 66123 Saarbrücken, Germany.
  • Kressler C; Experimental Rheumatology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • de Almeida M; Experimental Rheumatology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Bassler K; Life and Medical Sciences Institute, Genomics and Immunoregulation, University of Bonn, 53115 Bonn, Germany.
  • Ulas T; Life and Medical Sciences Institute, Genomics and Immunoregulation, University of Bonn, 53115 Bonn, Germany.
  • Schmidt F; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany; Excellence Cluster on Multimodal Computing and Interaction, Saarland University, 66123 Saarbrücken, Germany.
  • Xiong J; Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Glazar P; Systems Biology of Gene Regulatory Elements, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Klironomos F; Systems Biology of Gene Regulatory Elements, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Sinha A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24105 Kiel, Germany.
  • Kinkley S; Otto Warburg Laboratories: Epigenomics at Max Plank Institute for Molecular Genetics, 14195 Berlin, Germany.
  • Yang X; Otto Warburg Laboratories: Epigenomics at Max Plank Institute for Molecular Genetics, 14195 Berlin, Germany.
  • Arrigoni L; Max Planck Institute of Immunobiology and Epigenetics, 78108 Freiburg, Germany.
  • Amirabad AD; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany; Excellence Cluster on Multimodal Computing and Interaction, Saarland University, 66123 Saarbrücken, Germany.
  • Ardakani FB; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany; Excellence Cluster on Multimodal Computing and Interaction, Saarland University, 66123 Saarbrücken, Germany.
  • Feuerbach L; Applied Bioinformatics, Deutsches Krebsforschungszentrum, 59120 Heidelberg, Germany.
  • Gorka O; Institute for Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, Technical University 81675 Munich, Germany.
  • Ebert P; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany.
  • Müller F; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany.
  • Li N; Otto Warburg Laboratories: Epigenomics at Max Plank Institute for Molecular Genetics, 14195 Berlin, Germany.
  • Frischbutter S; Experimental Rheumatology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Schlickeiser S; Institute of Medical Immunology, Charité University Medicine, 13353 Berlin, Germany.
  • Cendon C; Cell Biology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Fröhler S; Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Felder B; Data Management and Genomics IT, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany.
  • Gasparoni N; Department of Genetics, University of Saarland, 66123 Saarbrücken, Germany.
  • Imbusch CD; Applied Bioinformatics, Deutsches Krebsforschungszentrum, 59120 Heidelberg, Germany.
  • Hutter B; Applied Bioinformatics, Deutsches Krebsforschungszentrum, 59120 Heidelberg, Germany.
  • Zipprich G; Data Management and Genomics IT, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany.
  • Tauchmann Y; Institut für Transfusionsmedizin, Charité University Medicine, 12203 Berlin, Germany.
  • Reinke S; Berlin-Brandenburg Center for Regenerative Therapies, 13353 Berlin, Germany.
  • Wassilew G; Center for Musculoskeletal Surgery, Charité University Medicine, 10117 Berlin, Germany.
  • Hoffmann U; Experimental Rheumatology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Richter AS; Max Planck Institute of Immunobiology and Epigenetics, 78108 Freiburg, Germany.
  • Sieverling L; Applied Bioinformatics, Deutsches Krebsforschungszentrum, 59120 Heidelberg, Germany.
  • Chang HD; Cell Biology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Syrbe U; Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité University Medicine, 12000 Berlin, Germany.
  • Kalus U; Institut für Transfusionsmedizin, Charité University Medicine, 12203 Berlin, Germany.
  • Eils J; Data Management and Genomics IT, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany.
  • Brors B; Applied Bioinformatics, Deutsches Krebsforschungszentrum, 59120 Heidelberg, Germany.
  • Manke T; Max Planck Institute of Immunobiology and Epigenetics, 78108 Freiburg, Germany.
  • Ruland J; Institute for Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, Technical University 81675 Munich, Germany; German Cancer Consortium (DKTK), 59120 Heidelberg, Germany; German Center for Infection Research (DZIF), partner site 81675 Munich, Germany.
  • Lengauer T; Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany.
  • Rajewsky N; Systems Biology of Gene Regulatory Elements, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Chen W; Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
  • Dong J; Cell Biology, German Rheumatism Research Centre, 10117 Berlin, Germany.
  • Sawitzki B; Institute of Medical Immunology, Charité University Medicine, 13353 Berlin, Germany.
Immunity ; 45(5): 1148-1161, 2016 11 15.
Article en En | MEDLINE | ID: mdl-27851915
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Diferenciación Celular / Epigénesis Genética / Epigenómica / Memoria Inmunológica Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Diferenciación Celular / Epigénesis Genética / Epigenómica / Memoria Inmunológica Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania