Maturation of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) in 3D collagen matrix: Effects of niche cell supplementation and mechanical stimulation.

Zhang, W; Kong, C W; Tong, M H; Chooi, W H; Huang, N; Li, R A; Chan, B P

Zhang, W; Kong, C W; Tong, M H; Chooi, W H; Huang, N; Li, R A; Chan, B P.

Afiliación

Zhang W; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Kong CW; Stem Cell and Regenerative Medicine Consortium, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Tong MH; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Chooi WH; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Huang N; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Li RA; Stem Cell and Regenerative Medicine Consortium, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Chan BP; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region. Electronic address: bpchan@hku.hk.

Acta Biomater ; 49: 204-217, 2017 02.

Article en En | MEDLINE | ID: mdl-27890729

Asunto(s)

Diferenciación Celular/efectos de los fármacos; Colágeno/farmacología; Células Madre Embrionarias Humanas/citología; Miocitos Cardíacos/citología; Nicho de Células Madre/efectos de los fármacos; Estrés Mecánico; Animales; Técnicas de Cocultivo; Regulación de la Expresión Génica/efectos de los fármacos; Células Madre Embrionarias Humanas/efectos de los fármacos; Células Madre Embrionarias Humanas/metabolismo; Humanos; Masculino; Células Madre Mesenquimatosas/citología; Células Madre Mesenquimatosas/efectos de los fármacos; Miocitos Cardíacos/efectos de los fármacos; Miocitos Cardíacos/metabolismo; Ratas; Ingeniería de Tejidos

Palabras clave

Heart tissue engineering; Human embryonic stem cell; Maturation; Mechanical loading; Mesenchymal cell

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Estrés Mecánico / Diferenciación Celular / Colágeno / Miocitos Cardíacos / Nicho de Células Madre / Células Madre Embrionarias Humanas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Acta Biomater Año: 2017 Tipo del documento: Article

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