Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

Yang, Cheng-Tao; Ma, Rui; Axton, Richard A; Jackson, Melany; Taylor, A Helen; Fidanza, Antonella; Marenah, Lamin; Frayne, Jan; Mountford, Joanne C; Forrester, Lesley M

Yang, Cheng-Tao; Ma, Rui; Axton, Richard A; Jackson, Melany; Taylor, A Helen; Fidanza, Antonella; Marenah, Lamin; Frayne, Jan; Mountford, Joanne C; Forrester, Lesley M.

Afiliación

Yang CT; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Ma R; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Axton RA; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Jackson M; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Taylor AH; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Fidanza A; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Marenah L; Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Frayne J; Scottish National Blood Transfusion Service, Scotland, United Kingdom.
Mountford JC; Department of Biochemistry, University of Bristol, United Kingdom.
Forrester LM; Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom.

Stem Cells ; 35(4): 886-897, 2017 04.

Article en En | MEDLINE | ID: mdl-28026072

Asunto(s)

Diferenciación Celular; Eritrocitos/citología; Eritrocitos/metabolismo; Células Madre Pluripotentes Inducidas/citología; Factores de Transcripción de Tipo Kruppel/metabolismo; Núcleo Celular/metabolismo; Proliferación Celular; Eritropoyesis/genética; Regulación de la Expresión Génica; Globinas/metabolismo; Células Madre Hematopoyéticas/citología; Células Madre Hematopoyéticas/metabolismo; Humanos; Células K562; Transporte de Proteínas; Proteínas Recombinantes de Fusión/metabolismo

Palabras clave

Erythroid differentiation; Gene delivery systems in vivo or in vitro; Induced pluripotent stem cells; Transcription factors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diferenciación Celular / Eritrocitos / Factores de Transcripción de Tipo Kruppel / Células Madre Pluripotentes Inducidas Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Stem Cells Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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