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Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis.
Hong, W David; Gibbons, Peter D; Leung, Suet C; Amewu, Richard; Stocks, Paul A; Stachulski, Andrew; Horta, Pedro; Cristiano, Maria L S; Shone, Alison E; Moss, Darren; Ardrey, Alison; Sharma, Raman; Warman, Ashley J; Bedingfield, Paul T P; Fisher, Nicholas E; Aljayyoussi, Ghaith; Mead, Sally; Caws, Maxine; Berry, Neil G; Ward, Stephen A; Biagini, Giancarlo A; O'Neill, Paul M; Nixon, Gemma L.
Afiliación
  • Hong WD; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Gibbons PD; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Leung SC; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Amewu R; Department of Chemistry, University of Ghana , P.O. Box LG56, Legon-Accra, Ghana.
  • Stocks PA; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Stachulski A; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Horta P; CCMAR and Department of Chemistry and Pharmacy, University of Algarve , 8005-139 Faro, Portugal.
  • Cristiano MLS; CCMAR and Department of Chemistry and Pharmacy, University of Algarve , 8005-139 Faro, Portugal.
  • Shone AE; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Moss D; School of Pharmacy, Keele University , Keele ST5 5BG, U.K.
  • Ardrey A; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Sharma R; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Warman AJ; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Bedingfield PTP; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Fisher NE; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Aljayyoussi G; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Mead S; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Caws M; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Berry NG; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Ward SA; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • Biagini GA; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, U.K.
  • O'Neill PM; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
  • Nixon GL; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
J Med Chem ; 60(9): 3703-3726, 2017 05 11.
Article en En | MEDLINE | ID: mdl-28304162

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolonas / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolonas / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido