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Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.
Klutzny, Saskia; Lesche, Ralf; Keck, Matthias; Kaulfuss, Stefan; Schlicker, Andreas; Christian, Sven; Sperl, Carolyn; Neuhaus, Roland; Mowat, Jeffrey; Steckel, Michael; Riefke, Björn; Prechtl, Stefan; Parczyk, Karsten; Steigemann, Patrick.
Afiliación
  • Klutzny S; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Lesche R; Department of Bioanalytics, Institute for Biotechnology, Technical University of Berlin, Berlin, Germany.
  • Keck M; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Kaulfuss S; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Schlicker A; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Christian S; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Sperl C; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Neuhaus R; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Mowat J; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Steckel M; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Riefke B; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Prechtl S; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Parczyk K; Drug Discovery, Bayer AG, Berlin 13353, Germany.
  • Steigemann P; Drug Discovery, Bayer AG, Berlin 13353, Germany.
Cell Death Dis ; 8(3): e2709, 2017 03 30.
Article en En | MEDLINE | ID: mdl-28358364

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esfingomielina Fosfodiesterasa / Neoplasias del Colon / Flufenazina / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esfingomielina Fosfodiesterasa / Neoplasias del Colon / Flufenazina / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: Alemania