HSYA alleviates secondary neuronal death through attenuating oxidative stress, inflammatory response, and neural apoptosis in SD rat spinal cord compression injury.

Pei, Jun-Peng; Fan, Li-Hong; Nan, Kai; Li, Jia; Dang, Xiao-Qian; Wang, Kun-Zheng

Pei, Jun-Peng; Fan, Li-Hong; Nan, Kai; Li, Jia; Dang, Xiao-Qian; Wang, Kun-Zheng.

Afiliación

Pei JP; Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China.
Fan LH; Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China. drfan2140@mail.xjtu.edu.cn.
Nan K; Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China.
Li J; Department of Orthopaedics, the First Affiliated Hospital of Xi'an Jiaotong University, School of Medicine, Xi'an, 710061, China.
Dang XQ; Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China.
Wang KZ; Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China.

J Neuroinflammation ; 14(1): 97, 2017 05 03.

Article en En | MEDLINE | ID: mdl-28468657

Asunto(s)

Apoptosis/fisiología; Chalcona/análogos & derivados; Mediadores de Inflamación/metabolismo; Neuronas/metabolismo; Estrés Oxidativo/fisiología; Quinonas/uso terapéutico; Compresión de la Médula Espinal/metabolismo; Animales; Apoptosis/efectos de los fármacos; Muerte Celular/efectos de los fármacos; Muerte Celular/fisiología; Chalcona/farmacología; Chalcona/uso terapéutico; Mediadores de Inflamación/antagonistas & inhibidores; Masculino; Neuronas/efectos de los fármacos; Neuronas/patología; Estrés Oxidativo/efectos de los fármacos; Pigmentos Biológicos/farmacología; Pigmentos Biológicos/uso terapéutico; Quinonas/farmacología; Ratas; Ratas Sprague-Dawley; Compresión de la Médula Espinal/tratamiento farmacológico

Palabras clave

Apoptosis; Cytokines; Hydroxysafflor yellow A (HSYA); Nuclear factor-kappa B (NF-κB); Oxidative stress; Spinal cord injury (SCI)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinonas / Compresión de la Médula Espinal / Chalcona / Apoptosis / Estrés Oxidativo / Mediadores de Inflamación / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2017 Tipo del documento: Article

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