Assessing the spectrum of germline variation in Fanconi anemia genes among patients with head and neck carcinoma before age 50.

Chandrasekharappa, Settara C; Chinn, Steven B; Donovan, Frank X; Chowdhury, Naweed I; Kamat, Aparna; Adeyemo, Adebowale A; Thomas, James W; Vemulapalli, Meghana; Hussey, Caroline S; Reid, Holly H; Mullikin, James C; Wei, Qingyi; Sturgis, Erich M

Chandrasekharappa, Settara C; Chinn, Steven B; Donovan, Frank X; Chowdhury, Naweed I; Kamat, Aparna; Adeyemo, Adebowale A; Thomas, James W; Vemulapalli, Meghana; Hussey, Caroline S; Reid, Holly H; Mullikin, James C; Wei, Qingyi; Sturgis, Erich M.

Afiliación

Chandrasekharappa SC; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Chinn SB; Department of Otolaryngology-Head and Neck Surgery, The University of Michigan, Ann Arbor, Michigan.
Donovan FX; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Chowdhury NI; Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas.
Kamat A; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Thomas JW; Intramural Sequencing Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Vemulapalli M; Intramural Sequencing Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Hussey CS; The University of Texas Health Science Center School of Medicine, Houston, Texas.
Reid HH; Department of Dermatology, The University of Texas Health Science Center School of Medicine, Houston, Texas.
Mullikin JC; Intramural Sequencing Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Wei Q; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Sturgis EM; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Cancer ; 123(20): 3943-3954, 2017 Oct 15.

Article en En | MEDLINE | ID: mdl-28678401

Asunto(s)

Carcinoma de Células Escamosas/genética; Anemia de Fanconi/genética; Neoplasias de Cabeza y Cuello/genética; Adulto; Edad de Inicio; Proteína BRCA2/genética; Análisis Mutacional de ADN; Proteína del Grupo de Complementación D2 de la Anemia de Fanconi/genética; Proteína del Grupo de Complementación E de la Anemia de Fanconi/genética; Proteína del Grupo de Complementación L de la Anemia de Fanconi/genética; Proteínas del Grupo de Complementación de la Anemia de Fanconi/genética; Femenino; Mutación de Línea Germinal; Heterocigoto; Secuenciación de Nucleótidos de Alto Rendimiento; Humanos; Masculino; Persona de Mediana Edad; Polimorfismo de Nucleótido Simple; Recombinasas/genética; Análisis de Secuencia de ADN; Carcinoma de Células Escamosas de Cabeza y Cuello

Palabras clave

Fanconi anemia; germline variations; head and neck cancers; recessive inherited disorders; squamous cell carcinoma

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Anemia de Fanconi / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Año: 2017 Tipo del documento: Article

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