Your browser doesn't support javascript.
loading
miRNAs in B-cell lymphoma: Molecular mechanisms and biomarker potential.
Solé, Carla; Larrea, Erika; Di Pinto, Giovanni; Tellaetxe, Maitena; Lawrie, Charles Henderson.
Afiliación
  • Solé C; Molecular Oncology Group, Biodonostia Research Institute, San Sebastián, Gipuzkoa, Spain.
  • Larrea E; Molecular Oncology Group, Biodonostia Research Institute, San Sebastián, Gipuzkoa, Spain.
  • Di Pinto G; Molecular Oncology Group, Biodonostia Research Institute, San Sebastián, Gipuzkoa, Spain.
  • Tellaetxe M; Molecular Oncology Group, Biodonostia Research Institute, San Sebastián, Gipuzkoa, Spain.
  • Lawrie CH; Molecular Oncology Group, Biodonostia Research Institute, San Sebastián, Gipuzkoa, Spain; Radcliffe Department of Medicine, University of Oxford, Oxford, UK; IKERBASQUE, Basque Foundation for Science, Bilbao, Bizkaia, Spain. Electronic address: charles.lawrie@biodonostia.org.
Cancer Lett ; 405: 79-89, 2017 10 01.
Article en En | MEDLINE | ID: mdl-28757417
ABSTRACT
MicroRNAs (miRNAs) are small non-coding RNAs that regulate many human genes including those involved in normal B-cell development. When these miRNAs are aberrantly expressed in B-cells they play key pathogenetic roles in the development and maintenance of B-cell lymphomas and by association may serve as useful biomarkers. In this review, we provide an overview of the importance of miRNAs to B-cell lymphomagenesis, as well as considering their use as biomarkers, and their potential usefulness for the clinic.
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Linfoma de Células B / MicroARNs Límite: Humans Idioma: En Revista: Cancer Lett Año: 2017 Tipo del documento: Article País de afiliación: España
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Linfoma de Células B / MicroARNs Límite: Humans Idioma: En Revista: Cancer Lett Año: 2017 Tipo del documento: Article País de afiliación: España