UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing.

Pan, Chenyu; Xiong, Yue; Lv, Xiangdong; Xia, Yuanxin; Zhang, Shuo; Chen, Hao; Fan, Jialin; Wu, Wenqing; Liu, Feng; Wu, Hailong; Zhou, Zhaocai; Zhang, Lei; Zhao, Yun

Pan, Chenyu; Xiong, Yue; Lv, Xiangdong; Xia, Yuanxin; Zhang, Shuo; Chen, Hao; Fan, Jialin; Wu, Wenqing; Liu, Feng; Wu, Hailong; Zhou, Zhaocai; Zhang, Lei; Zhao, Yun.

Afiliación

Pan C; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xiong Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Lv X; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xia Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhang S; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Chen H; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Fan J; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wu W; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Liu F; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wu H; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhou Z; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhang L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhao Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.

EMBO Rep ; 18(11): 1922-1934, 2017 11.

Article en En | MEDLINE | ID: mdl-28887318

Asunto(s)

Proteínas de Drosophila/genética; Drosophila melanogaster/genética; Regulación del Desarrollo de la Expresión Génica; Proteínas Hedgehog/genética; Procesamiento Proteico-Postraduccional; Enzimas Ubiquitina-Conjugadoras/genética; Pez Cebra/genética; Animales; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Secuencia Conservada; Proteínas de Unión al ADN/genética; Proteínas de Unión al ADN/metabolismo; Proteínas de Drosophila/metabolismo; Drosophila melanogaster/crecimiento & desarrollo; Drosophila melanogaster/metabolismo; Embrión no Mamífero; Proteínas Hedgehog/metabolismo; Discos Imaginales/crecimiento & desarrollo; Discos Imaginales/metabolismo; Larva/genética; Larva/crecimiento & desarrollo; Larva/metabolismo; Receptor Patched-2/genética; Receptor Patched-2/metabolismo; Poliubiquitina/genética; Poliubiquitina/metabolismo; Estabilidad Proteica; Proteolisis; Transducción de Señal; Factores de Transcripción/genética; Factores de Transcripción/metabolismo; Enzimas Ubiquitina-Conjugadoras/metabolismo; Ubiquitina-Proteína Ligasas/genética; Ubiquitina-Proteína Ligasas/metabolismo; Ubiquitinación; Pez Cebra/crecimiento & desarrollo; Pez Cebra/metabolismo; Proteínas de Pez Cebra/genética; Proteínas de Pez Cebra/metabolismo

Palabras clave

Drosophila; Ci; Hedgehog; UbcD1; ubiquitination

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pez Cebra / Procesamiento Proteico-Postraduccional / Regulación del Desarrollo de la Expresión Génica / Proteínas de Drosophila / Enzimas Ubiquitina-Conjugadoras / Drosophila melanogaster / Proteínas Hedgehog Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: China

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