P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis.

Luo, Weifeng; Feldman, Daniel; McCallister, Reid; Brophy, Colleen; Cheung-Flynn, Joyce

Luo, Weifeng; Feldman, Daniel; McCallister, Reid; Brophy, Colleen; Cheung-Flynn, Joyce.

Afiliación

Luo W; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Feldman D; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
McCallister R; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Brophy C; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Cheung-Flynn J; VA Tennessee Valley Healthcare System, Nashville, TN, USA.

Purinergic Signal ; 13(4): 579-590, 2017 Dec.

Article en En | MEDLINE | ID: mdl-28905300

Asunto(s)

Antagonistas del Receptor Purinérgico P2X/farmacología; Receptores Purinérgicos P2X7/metabolismo; Vena Safena/trasplante; Manejo de Especímenes/efectos adversos; Animales; Aorta/efectos de los fármacos; Aorta/metabolismo; Apoptosis/efectos de los fármacos; Puente de Arteria Coronaria/métodos; Femenino; Humanos; Masculino; Ratas; Ratas Sprague-Dawley; Vena Safena/efectos de los fármacos; Vena Safena/metabolismo; Manejo de Especímenes/métodos

Palabras clave

ATP; Apoptosis; P2X7 receptor; Purinergic signaling; Saphenous vein graft; Subfailure overstretch; Vascular injury

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vena Safena / Manejo de Especímenes / Receptores Purinérgicos P2X7 / Antagonistas del Receptor Purinérgico P2X Límite: Animals / Female / Humans / Male Idioma: En Revista: Purinergic Signal Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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