Efficient generation of the mouse model with a defined point mutation through haploid cell-mediated gene editing.

Wei, Leixin; Wang, Xiukun; Yang, Suming; Yuan, Wen; Li, Jinsong

Wei, Leixin; Wang, Xiukun; Yang, Suming; Yuan, Wen; Li, Jinsong.

Afiliación

Wei L; Department of Orthopaedic Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biolog
Wang X; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China.
Yang S; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China.
Yuan W; Department of Orthopaedic Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China. Electronic address: yuanwenspine@163.com.
Li J; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: j

J Genet Genomics ; 44(9): 461-463, 2017 09 20.

Article en En | MEDLINE | ID: mdl-28943147

Asunto(s)

Edición Génica/métodos; Haploidia; Mutación Puntual/genética; Animales; Secuencia de Bases; Sistemas CRISPR-Cas/genética; Ratones; Modelos Animales

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutación Puntual / Edición Génica / Haploidia Límite: Animals Idioma: En Revista: J Genet Genomics Año: 2017 Tipo del documento: Article

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