Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition.

Suzuki, Toshio; Tada, Yuji; Gladson, Santhi; Nishimura, Rintaro; Shimomura, Iwao; Karasawa, Satoshi; Tatsumi, Koichiro; West, James

Suzuki, Toshio; Tada, Yuji; Gladson, Santhi; Nishimura, Rintaro; Shimomura, Iwao; Karasawa, Satoshi; Tatsumi, Koichiro; West, James.

Afiliación

Suzuki T; Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. toshio.suzuki@vanderbilt.edu.
Tada Y; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan. toshio.suzuki@vanderbilt.edu.
Gladson S; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Nishimura R; Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Shimomura I; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Karasawa S; Department of Advanced Medicine in Pulmonary Hypertension, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tatsumi K; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
West J; Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Respir Res ; 18(1): 177, 2017 10 16.

Article en En | MEDLINE | ID: mdl-29037205

Asunto(s)

Adamantano/análogos & derivados; Transición Epitelial-Mesenquimal/efectos de los fármacos; Lipopolisacáridos/toxicidad; Lesión Pulmonar/tratamiento farmacológico; Nitrilos/uso terapéutico; Fibrosis Pulmonar/tratamiento farmacológico; Pirrolidinas/uso terapéutico; Adamantano/farmacología; Adamantano/uso terapéutico; Animales; Inhibidores de la Dipeptidil-Peptidasa IV/farmacología; Inhibidores de la Dipeptidil-Peptidasa IV/uso terapéutico; Transición Epitelial-Mesenquimal/fisiología; Lesión Pulmonar/inducido químicamente; Lesión Pulmonar/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Nitrilos/farmacología; Fibrosis Pulmonar/inducido químicamente; Fibrosis Pulmonar/metabolismo; Pirrolidinas/farmacología; Vildagliptina

Palabras clave

Dipeptidyl peptidase 4; Endothelial-to-mesenchymal transition; Post ARDS pulmonary fibrosis; Pulmonary fibrosis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis Pulmonar / Pirrolidinas / Adamantano / Lipopolisacáridos / Lesión Pulmonar / Transición Epitelial-Mesenquimal / Nitrilos Límite: Animals Idioma: En Revista: Respir Res Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google