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Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.
Adalsteinsson, Viktor A; Ha, Gavin; Freeman, Samuel S; Choudhury, Atish D; Stover, Daniel G; Parsons, Heather A; Gydush, Gregory; Reed, Sarah C; Rotem, Denisse; Rhoades, Justin; Loginov, Denis; Livitz, Dimitri; Rosebrock, Daniel; Leshchiner, Ignaty; Kim, Jaegil; Stewart, Chip; Rosenberg, Mara; Francis, Joshua M; Zhang, Cheng-Zhong; Cohen, Ofir; Oh, Coyin; Ding, Huiming; Polak, Paz; Lloyd, Max; Mahmud, Sairah; Helvie, Karla; Merrill, Margaret S; Santiago, Rebecca A; O'Connor, Edward P; Jeong, Seong H; Leeson, Rachel; Barry, Rachel M; Kramkowski, Joseph F; Zhang, Zhenwei; Polacek, Laura; Lohr, Jens G; Schleicher, Molly; Lipscomb, Emily; Saltzman, Andrea; Oliver, Nelly M; Marini, Lori; Waks, Adrienne G; Harshman, Lauren C; Tolaney, Sara M; Van Allen, Eliezer M; Winer, Eric P; Lin, Nancy U; Nakabayashi, Mari; Taplin, Mary-Ellen; Johannessen, Cory M.
Afiliación
  • Adalsteinsson VA; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA. viktor@broadinstitute.org.
  • Ha G; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, 02142, MA, USA. viktor@broadinstitute.org.
  • Freeman SS; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Choudhury AD; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Stover DG; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Parsons HA; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Gydush G; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Reed SC; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Rotem D; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Rhoades J; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Loginov D; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Livitz D; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Rosebrock D; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Leshchiner I; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Kim J; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Stewart C; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Rosenberg M; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Francis JM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, 02142, MA, USA.
  • Zhang CZ; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Cohen O; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Oh C; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Ding H; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Polak P; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Lloyd M; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Mahmud S; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Helvie K; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Merrill MS; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Santiago RA; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • O'Connor EP; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Jeong SH; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Leeson R; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Barry RM; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Kramkowski JF; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Zhang Z; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, 02142, MA, USA.
  • Polacek L; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
  • Lohr JG; Harvard Medical School, 250 Longwood Avenue, Boston, 02115, MA, USA.
  • Schleicher M; Massachusetts General Hospital, 55 Fruit Street, Boston, 02129, MA, USA.
  • Lipscomb E; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Saltzman A; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Oliver NM; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Marini L; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Waks AG; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Harshman LC; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Tolaney SM; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Van Allen EM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, 02142, MA, USA.
  • Winer EP; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, 02142, MA, USA.
  • Lin NU; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Nakabayashi M; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Taplin ME; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, 02215, MA, USA.
  • Johannessen CM; Eli and Edythe L. Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, 02142, MA, USA.
Nat Commun ; 8(1): 1324, 2017 11 06.
Article en En | MEDLINE | ID: mdl-29109393
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN de Neoplasias / Ácidos Nucleicos Libres de Células / Secuenciación del Exoma / Metástasis de la Neoplasia Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN de Neoplasias / Ácidos Nucleicos Libres de Células / Secuenciación del Exoma / Metástasis de la Neoplasia Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos