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Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.
Altintop, Mehlika Dilek; Ciftci, Halil Ibrahim; Radwan, Mohamed O; Sever, Belgin; Kaplancikli, Zafer Asim; Ali, Taha F S; Koga, Ryoko; Fujita, Mikako; Otsuka, Masami; Özdemir, Ahmet.
Afiliación
  • Altintop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey. mdaltintop@anadolu.edu.tr.
  • Ciftci HI; Department of Bioorganic Medicinal Chemistry, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan. hiciftci@kumamoto-u.ac.jp.
  • Radwan MO; Stanford PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA. hiciftci@kumamoto-u.ac.jp.
  • Sever B; Department of Bioorganic Medicinal Chemistry, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan. mohamedosman251@gmail.com.
  • Kaplancikli ZA; Department of Chemistry of Natural Compounds, National Research Center, Dokki, 12622 Cairo, Egypt. mohamedosman251@gmail.com.
  • Ali TFS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey. belginsever@anadolu.edu.tr.
  • Koga R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey. zakaplan@anadolu.edu.tr.
  • Fujita M; Department of Bioorganic Medicinal Chemistry, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan. tahafarouk1@yahoo.com.
  • Otsuka M; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt. tahafarouk1@yahoo.com.
  • Özdemir A; Department of Bioorganic Medicinal Chemistry, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan. kk1205@kumamoto-u.ac.jp.
Molecules ; 23(1)2017 Dec 27.
Article en En | MEDLINE | ID: mdl-29280989
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiadiazoles / Leucemia Mielógena Crónica BCR-ABL Positiva / Antineoplásicos Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Turquía
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiadiazoles / Leucemia Mielógena Crónica BCR-ABL Positiva / Antineoplásicos Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Turquía