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A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target.
Ibhazehiebo, Kingsley; Gavrilovici, Cezar; de la Hoz, Cristiane L; Ma, Shun-Chieh; Rehak, Renata; Kaushik, Gaurav; Meza Santoscoy, Paola L; Scott, Lucas; Nath, Nandan; Kim, Do-Young; Rho, Jong M; Kurrasch, Deborah M.
Afiliación
  • Ibhazehiebo K; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.
  • Gavrilovici C; Alberta Children's Hospital Research Institute, University of Calgary, Canada.
  • de la Hoz CL; Alberta Children's Hospital Research Institute, University of Calgary, Canada.
  • Ma SC; Departments of Pediatrics, Clinical Neurosciences, Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Canada.
  • Rehak R; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.
  • Kaushik G; Alberta Children's Hospital Research Institute, University of Calgary, Canada.
  • Meza Santoscoy PL; Departments of Neurology and Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
  • Scott L; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.
  • Nath N; Alberta Children's Hospital Research Institute, University of Calgary, Canada.
  • Kim DY; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.
  • Rho JM; Alberta Children's Hospital Research Institute, University of Calgary, Canada.
  • Kurrasch DM; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Brain ; 141(3): 744-761, 2018 03 01.
Article en En | MEDLINE | ID: mdl-29373639
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Convulsiones / Histona Desacetilasas Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Brain Año: 2018 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Convulsiones / Histona Desacetilasas Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Brain Año: 2018 Tipo del documento: Article País de afiliación: Canadá