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Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.
Chung, Liam; Thiele Orberg, Erik; Geis, Abby L; Chan, June L; Fu, Kai; DeStefano Shields, Christina E; Dejea, Christine M; Fathi, Payam; Chen, Jie; Finard, Benjamin B; Tam, Ada J; McAllister, Florencia; Fan, Hongni; Wu, Xinqun; Ganguly, Sudipto; Lebid, Andriana; Metz, Paul; Van Meerbeke, Sara W; Huso, David L; Wick, Elizabeth C; Pardoll, Drew M; Wan, Fengyi; Wu, Shaoguang; Sears, Cynthia L; Housseau, Franck.
Afiliación
  • Chung L; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA; Translational Tissue Engineering Center, Wilmer Eye Ins
  • Thiele Orberg E; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Geis AL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Chan JL; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Fu K; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
  • DeStefano Shields CE; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Dejea CM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Fathi P; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Chen J; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Finard BB; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Tam AJ; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • McAllister F; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Fan H; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Wu X; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Ganguly S; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Lebid A; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Metz P; Department of Pathology, Radboud University Medical Centre, Geert Grooteplein-Zuid 10, 6525 GA, Nijmegen, Netherlands.
  • Van Meerbeke SW; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Huso DL; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Wick EC; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Pardoll DM; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA.
  • Wan F; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Biochemistry and Molecula
  • Wu S; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Sears CL; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA; Department of Molecular Microbiology and Immunology, Bl
  • Housseau F; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA. Electronic address: fhousse1@jhmi.edu.
Cell Host Microbe ; 23(2): 203-214.e5, 2018 Feb 14.
Article en En | MEDLINE | ID: mdl-29398651
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Bacteroides fragilis / Metaloendopeptidasas / Neoplasias Colorrectales / Colon / Interleucina-17 / Células Epiteliales / Factor de Transcripción ReIA / Carcinogénesis Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Bacteroides fragilis / Metaloendopeptidasas / Neoplasias Colorrectales / Colon / Interleucina-17 / Células Epiteliales / Factor de Transcripción ReIA / Carcinogénesis Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article