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Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs.
Montag, J; Petersen, B; Flögel, A K; Becker, E; Lucas-Hahn, A; Cost, G J; Mühlfeld, C; Kraft, T; Niemann, H; Brenner, B.
Afiliación
  • Montag J; Institute for Molecular and Cell Physiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Montag.Judith@mh-hannover.de.
  • Petersen B; Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Hoeltystrasse 10, Mariensee, 31535, Neustadt, Germany.
  • Flögel AK; REBIRTH, Cluster of Excellence, Hannover Medical School, Hannover, 30625, Germany.
  • Becker E; Institute for Molecular and Cell Physiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
  • Lucas-Hahn A; Institute for Molecular and Cell Physiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
  • Cost GJ; Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Hoeltystrasse 10, Mariensee, 31535, Neustadt, Germany.
  • Mühlfeld C; Sangamo Therapeutics, 501 Canal Boulevard, CA, 94804, Richmond, USA.
  • Kraft T; Casebia Therapeutics, 455 Mission Bay Boulevard South, San Francisco, CA, 94158, USA.
  • Niemann H; Institute of Functional and Applied Anatomy, Hannover Medical School Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
  • Brenner B; Institute for Molecular and Cell Physiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Sci Rep ; 8(1): 4786, 2018 03 19.
Article en En | MEDLINE | ID: mdl-29555974

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cadenas Pesadas de Miosina / Miosinas Cardíacas / Técnicas de Sustitución del Gen / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Cadenas Pesadas de Miosina / Miosinas Cardíacas / Técnicas de Sustitución del Gen / Mutación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Alemania