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Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts.
de Las Rivas, Matilde; Coelho, Helena; Diniz, Ana; Lira-Navarrete, Erandi; Compañón, Ismael; Jiménez-Barbero, Jesús; Schjoldager, Katrine T; Bennett, Eric P; Vakhrushev, Sergey Y; Clausen, Henrik; Corzana, Francisco; Marcelo, Filipa; Hurtado-Guerrero, Ramon.
Afiliación
  • de Las Rivas M; Instituto de Biocomputación y Fisica de Sistemas Complejos (BIFI), BIFI-IQFR (CSIC) Joint Unit, Universidad de Zaragoza, 50018, Zaragoza, Spain.
  • Coelho H; UCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516, Caparica, Portugal.
  • Diniz A; CIC bioGUNE, Bizkaia Technology Park, Building 801A, 48170, Derio, Spain.
  • Lira-Navarrete E; Department of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country, 48940, Leioa, Bizkaia, Spain.
  • Compañón I; UCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516, Caparica, Portugal.
  • Jiménez-Barbero J; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, School of Dentistry, University of Copenhagen, Copenhagen, Denmark.
  • Schjoldager KT; Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química, E-26006, Logroño, Spain.
  • Bennett EP; CIC bioGUNE, Bizkaia Technology Park, Building 801A, 48170, Derio, Spain.
  • Vakhrushev SY; Department of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country, 48940, Leioa, Bizkaia, Spain.
  • Clausen H; Ikerbasque, Basque Foundation for Science, Maria Diaz de Haro 13, 48009, Bilbao, Spain.
  • Corzana F; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, School of Dentistry, University of Copenhagen, Copenhagen, Denmark.
  • Marcelo F; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, School of Dentistry, University of Copenhagen, Copenhagen, Denmark.
  • Hurtado-Guerrero R; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, School of Dentistry, University of Copenhagen, Copenhagen, Denmark.
Chemistry ; 24(33): 8382-8392, 2018 Jun 12.
Article en En | MEDLINE | ID: mdl-29601100
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Uridina Difosfato / N-Acetilgalactosaminiltransferasas / Mucina-1 / Mucinas Límite: Humans Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: España
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Uridina Difosfato / N-Acetilgalactosaminiltransferasas / Mucina-1 / Mucinas Límite: Humans Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: España