Valproate and epilepsy: for women as well as men.
Pract Neurol
; 18(3): 222-223, 2018 Jun.
Article
en En
| MEDLINE
| ID: mdl-29686036
ABSTRACT
Sodium valproate remains the best drug for idiopathic generalised epilepsy. For men with the latter diagnosis, this is the drug of choice. Sodium valproate has an unacceptably high level of major fetal malformation and also causes learning disabilities in many children exposed to the drug in utero. Women of reproductive age should not normally be offered this drug. There are many women with refractory epilepsy who would benefit from this drug and who are not planning pregnancy. Individualised epilepsy care is the gold standard, not blanket bans on drug choice based on gender.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ácido Valproico
/
Epilepsia
/
Anticonvulsivantes
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Pract Neurol
Año:
2018
Tipo del documento:
Article