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Ganetespib targets multiple levels of the receptor tyrosine kinase signaling cascade and preferentially inhibits ErbB2-overexpressing breast cancer cells.
Lee, Harry; Saini, Nipun; Howard, Erin W; Parris, Amanda B; Ma, Zhikun; Zhao, Qingxia; Zhao, Ming; Liu, Bolin; Edgerton, Susan M; Thor, Ann D; Yang, Xiaohe.
Afiliación
  • Lee H; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Saini N; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Howard EW; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Parris AB; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Ma Z; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Zhao Q; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Zhao M; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
  • Liu B; Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Edgerton SM; Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Thor AD; Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Yang X; Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA. xyang@nccu.edu.
Sci Rep ; 8(1): 6829, 2018 05 01.
Article en En | MEDLINE | ID: mdl-29717218
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triazoles / Neoplasias de la Mama / Proteínas Tirosina Quinasas Receptoras / Receptor ErbB-2 / Proteínas HSP90 de Choque Térmico / Lapatinib / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triazoles / Neoplasias de la Mama / Proteínas Tirosina Quinasas Receptoras / Receptor ErbB-2 / Proteínas HSP90 de Choque Térmico / Lapatinib / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos