Sentinel Lymph Node Biopsy in Breast Cancer Patients by Means of Indocyanine Green Using the Karl Storz VITOM® Fluorescence Camera.
Biomed Res Int
; 2018: 6251468, 2018.
Article
en En
| MEDLINE
| ID: mdl-29780827
ABSTRACT
Currently, the use of radioisotope and blue dye for sentinel lymph node biopsy (SLNB) for axillary staging in breast cancer is common. Recently, indocyanine green (ICG) has been proposed as an alternative sentinel lymph node (SLN) tracking agent. We evaluated the clinical value of ICG as an additional tracer in combination with Technetium99m and as an alternative to Technetium99m for the identification of SLN in 104 breast cancer patients. 21 patients had at least 1 histologically tumor-positive SLN. All 21 patients were detected by ICG; in one of these 21 sentinel-positive patients, Technetium99m was unable to identify lymph node involvement. Our results show that ICG is as effective as the radioisotope for SLNB. In addition, as a near-infrared dye, it has the advantages of real-time visualization, lower cost, and wider availability, since no radioactive material needs to be handled. This trial is registered with German Clinical Trial Register Main ID DRKS00013606.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Coloración y Etiquetado
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Neoplasias de la Mama
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Biopsia del Ganglio Linfático Centinela
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Rastreo Celular
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Verde de Indocianina
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Biomed Res Int
Año:
2018
Tipo del documento:
Article
País de afiliación:
Alemania