Control of pathogens and microbiota by innate lymphoid cells.
Microbes Infect
; 20(6): 317-322, 2018.
Article
en En
| MEDLINE
| ID: mdl-29852240
ABSTRACT
Innate lymphoid cells (ILCs) are the innate counterpart of T cells. Upon infection or injury, ILCs react promptly to direct the developing immune response to the one most adapted to the threat facing the organism. Therefore, ILCs play an important role early in resistance to infection, but also to maintain homeostasis with the symbiotic microbiota following perturbations induced by diet and pathogens. Such roles of ILCs have been best characterized in the intestine and lung, mucosal sites that are exposed to the environment and are therefore colonized with diverse but specific types of microbes. Understanding the dialogue between pathogens, microbiota and ILCs may lead to new strategies to re-inforce immunity for prevention, vaccination and therapy.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos
/
Interacciones Huésped-Patógeno
/
Microbiota
/
Inmunidad Innata
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Microbes Infect
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
MICROBIOLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Francia