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Mechanisms of precipitate formation during the purification of an Fc-fusion protein.
Greene, Daniel G; Traylor, Steven J; Guo, Jing; Choe, Leila H; Modla, Shannon; Xu, Xuankuo; Singh, Nripen; Lock, Lye Lin; Ghose, Sanchayita; Li, Zheng Jian; Lee, Kelvin H; Wagner, Norman J; Lenhoff, Abraham M.
Afiliación
  • Greene DG; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware.
  • Traylor SJ; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Guo J; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware.
  • Choe LH; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware.
  • Modla S; Delaware Biotechnology Institute, Newark, Delaware.
  • Xu X; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Singh N; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Lock LL; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Ghose S; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Li ZJ; Biologics Process Development, Global Product Development and Supply, Bristol-Myers Squibb Company, Devens, Massachusetts.
  • Lee KH; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware.
  • Wagner NJ; Delaware Biotechnology Institute, Newark, Delaware.
  • Lenhoff AM; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware.
Biotechnol Bioeng ; 115(10): 2489-2503, 2018 Oct.
Article en En | MEDLINE | ID: mdl-29896879

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Proteómica / Precipitación Fraccionada / Modelos Químicos Límite: Animals Idioma: En Revista: Biotechnol Bioeng Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Proteómica / Precipitación Fraccionada / Modelos Químicos Límite: Animals Idioma: En Revista: Biotechnol Bioeng Año: 2018 Tipo del documento: Article