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Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.
Amberg, Willi; Lange, Udo E W; Ochse, Michael; Pohlki, Frauke; Behl, Berthold; Relo, Ana Lucia; Hornberger, Wilfried; Hoft, Carolin; Mezler, Mario; Sydor, Jens; Wang, Ying; Zhao, Hongyu; Brewer, Jason T; Dietrich, Justin; Li, Huanqiu; Akritopoulou-Zanze, Irini; Lao, Yanbin; Hannick, Steven M; Ku, Yi-Yin; Vasudevan, Anil.
Afiliación
  • Amberg W; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Lange UEW; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Ochse M; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Pohlki F; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Behl B; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Relo AL; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Hornberger W; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Hoft C; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Mezler M; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Sydor J; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Wang Y; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Zhao H; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Brewer JT; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Dietrich J; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Li H; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Akritopoulou-Zanze I; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Lao Y; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Hannick SM; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Ku YY; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Vasudevan A; AbbVie Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
J Med Chem ; 61(17): 7503-7524, 2018 09 13.
Article en En | MEDLINE | ID: mdl-30080045
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tetrahidronaftalenos / Encéfalo / Cromanos / Proteínas de Transporte de Glicina en la Membrana Plasmática Límite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tetrahidronaftalenos / Encéfalo / Cromanos / Proteínas de Transporte de Glicina en la Membrana Plasmática Límite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania