Sweet Solutions for Analgesia in Neonates in China: A Systematic Review and Meta-Analysis.
Can J Nurs Res
; 51(2): 116-127, 2019 Jun.
Article
en En
| MEDLINE
| ID: mdl-30466313
ABSTRACT
INTRODUCTION:
High-quality synthesized evidence of sweet taste analgesia in neonates exists. However, Chinese databases have never been included in previous systematic reviews of sweet solutions for procedural pain.OBJECTIVE:
To conduct a systematic review of Chinese literature evaluating analgesic effects of sweet solutions for neonates. Data sources Wang Fang, China National Knowledge Infrastructure and Chinese Biomedical Literature Database. Data extraction andanalysis:
Two authors screened studies for inclusion and conducted risk of bias ratings and data extraction. A third author resolved any conflicts. Meta-analyses were performed using RevMan 5.2 software, on mean differences in pain outcomes using random effects models.RESULTS:
Thirty-one trials (4999 neonates) were included; 26 trials used glucose, 4 used sucrose, and 1 trial evaluated both solutions. Sweet solutions reduced standardized mean pain scores (n = 21 studies; -1.68, 95% confidence interval -2.08, -1.27) and cry duration (n = 6 studies; -25.60, 95% confidence interval -36.47, -14.72 s) but not heart rate change (n = 7 studies; -17.64, 95% confidence interval -52.71, 17.43). No included studies cited the previously published systematic reviews of sweet solutions.CONCLUSIONS:
This systematic review of Chinese databases showed the same results as previously published systematic reviews. No trials included in this review cited the English systematic reviews, highlighting a parallel research agenda.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Edulcorantes
/
Analgésicos
Tipo de estudio:
Prognostic_studies
/
Systematic_reviews
Límite:
Humans
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
Can J Nurs Res
Asunto de la revista:
ENFERMAGEM
Año:
2019
Tipo del documento:
Article
País de afiliación:
China