Suppression of the SAP18/HDAC1 complex by targeting TRIM56 and Nanog is essential for oncogenic viral FLICE-inhibitory protein-induced acetylation of p65/RelA, NF-&#954;B activation, and promotion of cell invasion and angiogenesis.

Ding, Xiangya; Xu, Jingyun; Wang, Cong; Feng, Qi; Wang, Qingxia; Yang, Yue; Lu, Hongmei; Wang, Fei; Zhu, Kaixiang; Li, Wan; Yan, Qin; Gao, Shou-Jiang; Lu, Chun

Suppression of the SAP18/HDAC1 complex by targeting TRIM56 and Nanog is essential for oncogenic viral FLICE-inhibitory protein-induced acetylation of p65/RelA, NF-κB activation, and promotion of cell invasion and angiogenesis.

Ding, Xiangya; Xu, Jingyun; Wang, Cong; Feng, Qi; Wang, Qingxia; Yang, Yue; Lu, Hongmei; Wang, Fei; Zhu, Kaixiang; Li, Wan; Yan, Qin; Gao, Shou-Jiang; Lu, Chun.

Afiliación

Ding X; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, 211166, P. R. China.
Xu J; Key Laboratory of Pathogen Biology of Jiangsu Province, Nanjing Medical University, Nanjing, 211166, P. R. China.
Wang C; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Feng Q; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Wang Q; Department of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, P. R. China.
Yang Y; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Lu H; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Wang F; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Zhu K; Department of Obstetrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, P. R. China.
Li W; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Yan Q; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Gao SJ; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.
Lu C; Department of Microbiology, Nanjing Medical University, Nanjing, 211166, P. R. China.

Cell Death Differ ; 26(10): 1970-1986, 2019 10.

Article en En | MEDLINE | ID: mdl-30670829

Asunto(s)

Proteína Reguladora de Apoptosis Similar a CASP8 y FADD/metabolismo; Histona Desacetilasa 1/metabolismo; FN-kappa B/metabolismo; Proteína Homeótica Nanog/metabolismo; Sarcoma de Kaposi/irrigación sanguínea; Sarcoma de Kaposi/metabolismo; Proteínas de Motivos Tripartitos/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Acetilación; Animales; Movimiento Celular; Embrión de Pollo; Proteínas Co-Represoras/genética; Proteínas Co-Represoras/metabolismo; Células Endoteliales/metabolismo; Células HEK293; Histona Desacetilasa 1/genética; Células Endoteliales de la Vena Umbilical Humana; Humanos; Masculino; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Proteína Homeótica Nanog/genética; Invasividad Neoplásica; Neovascularización Patológica/metabolismo; Proteínas de Unión al ARN/genética; Proteínas de Unión al ARN/metabolismo; Sarcoma de Kaposi/genética; Sarcoma de Kaposi/patología; Transducción de Señal; Factor de Transcripción ReIA/metabolismo; Proteínas de Motivos Tripartitos/genética; Ubiquitina-Proteína Ligasas/genética; Proteínas Virales/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sarcoma de Kaposi / FN-kappa B / Ubiquitina-Proteína Ligasas / Proteína Reguladora de Apoptosis Similar a CASP8 y FADD / Histona Desacetilasa 1 / Proteína Homeótica Nanog / Proteínas de Motivos Tripartitos Límite: Animals / Humans / Male Idioma: En Revista: Cell Death Differ Año: 2019 Tipo del documento: Article

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