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Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.
Kennedy, Nicholas A; Heap, Graham A; Green, Harry D; Hamilton, Benjamin; Bewshea, Claire; Walker, Gareth J; Thomas, Amanda; Nice, Rachel; Perry, Mandy H; Bouri, Sonia; Chanchlani, Neil; Heerasing, Neel M; Hendy, Peter; Lin, Simeng; Gaya, Daniel R; Cummings, J R Fraser; Selinger, Christian P; Lees, Charlie W; Hart, Ailsa L; Parkes, Miles; Sebastian, Shaji; Mansfield, John C; Irving, Peter M; Lindsay, James; Russell, Richard K; McDonald, Timothy J; McGovern, Dermot; Goodhand, James R; Ahmad, Tariq.
Afiliación
  • Kennedy NA; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK; Institute of Genetic and Molecular Medicine, University of Edinburgh, E
  • Heap GA; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Green HD; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Hamilton B; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Bewshea C; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Walker GJ; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Thomas A; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Nice R; Department of Blood Science, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Perry MH; Department of Blood Science, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Bouri S; Department of Gastroenterology, St Mark's Hospital, London North West Healthcare NHS Trust, Harrow, UK.
  • Chanchlani N; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Heerasing NM; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Hendy P; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • Lin S; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Gaya DR; Department of Gastroenterology, Glasgow Royal Infirmary, NHS Greater Glasgow and Clyde, Glasgow, UK.
  • Cummings JRF; Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Experimental Medicine, University of Southampton, Southampton, UK.
  • Selinger CP; Leeds Gastroenterology Institute, Leeds Teaching Hospitals NHS Trust, St James University Hospital, Leeds, UK.
  • Lees CW; Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK; Department of Gastroenterology, Western General Hospital, NHS Lothian, Edinburgh, UK.
  • Hart AL; Department of Gastroenterology, St Mark's Hospital, London North West Healthcare NHS Trust, Harrow, UK.
  • Parkes M; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Sebastian S; Gastroenterology and Hepatology, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK.
  • Mansfield JC; Department of Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Irving PM; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Lindsay J; Department of Gastroenterology, The Royal London Hospital, Barts Health NHS Trust, London, UK.
  • Russell RK; Department of Paediatric Gastroenterology, Royal Hospital for Children UK, NHS Greater Glasgow and Clyde, Glasgow, UK.
  • McDonald TJ; Department of Blood Science, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK.
  • McGovern D; F Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Goodhand JR; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK.
  • Ahmad T; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service (NHS) Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK. Electronic address: tariq.ahmad1@nhs.net.
Lancet Gastroenterol Hepatol ; 4(5): 341-353, 2019 05.
Article en En | MEDLINE | ID: mdl-30824404
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Crohn / Adalimumab / Infliximab / Inhibidores del Factor de Necrosis Tumoral Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Gastroenterol Hepatol Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Crohn / Adalimumab / Infliximab / Inhibidores del Factor de Necrosis Tumoral Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Gastroenterol Hepatol Año: 2019 Tipo del documento: Article