The Familial dementia gene ITM2b/BRI2 facilitates glutamate transmission via both presynaptic and postsynaptic mechanisms.

Yao, Wen; Yin, Tao; Tambini, Marc D; D'Adamio, Luciano

Yao, Wen; Yin, Tao; Tambini, Marc D; D'Adamio, Luciano.

Afiliación

Yao W; Department of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 185 South Orange Ave, Newark, NJ, 07103, USA.
Yin T; Department of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 185 South Orange Ave, Newark, NJ, 07103, USA.
Tambini MD; Department of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 185 South Orange Ave, Newark, NJ, 07103, USA.
D'Adamio L; Department of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 185 South Orange Ave, Newark, NJ, 07103, USA. luciano.dadam

Sci Rep ; 9(1): 4862, 2019 03 19.

Article en En | MEDLINE | ID: mdl-30890756

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/genética; Demencia/genética; Ácido Glutámico/metabolismo; Animales; Demencia/patología; Modelos Animales de Enfermedad; Ácido Glutámico/genética; Hipocampo/metabolismo; Humanos; Potenciación a Largo Plazo/genética; Ratones; Ratones Noqueados; Mutación/genética; Neuronas/metabolismo; Neuronas/patología; Terminales Presinápticos/metabolismo; ARN Mensajero/genética; Potenciales Sinápticos/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácido Glutámico / Demencia / Proteínas Adaptadoras Transductoras de Señales Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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