Triptolide Suppresses Growth of Breast Cancer by Targeting HMGB1 in Vitro and in Vivo.

Jiang, Wei; Chen, Maojian; Xiao, Chanchan; Yang, Weiping; Qin, Qinghong; Tan, Qixing; Liang, Zhijie; Liao, Xiaoli; Mao, Anyun; Wei, Changyuan

Jiang, Wei; Chen, Maojian; Xiao, Chanchan; Yang, Weiping; Qin, Qinghong; Tan, Qixing; Liang, Zhijie; Liao, Xiaoli; Mao, Anyun; Wei, Changyuan.

Afiliación

Jiang W; Department of Medical Oncology, The Affiliated Tumor Hospital of Guangxi Medical University.
Chen M; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.
Xiao C; Department of Experimental Research, The Affiliated Tumor Hospital of Guangxi Medical University.
Yang W; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.
Qin Q; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.
Tan Q; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.
Liang Z; Department of Breast and Thyroid Surgery, The Fifth Affliated Hospital of Guangxi Medical University & The First People's Hospital of Nanning.
Liao X; Department of Medical Oncology, The Affiliated Tumor Hospital of Guangxi Medical University.
Mao A; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.
Wei C; Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University.

Biol Pharm Bull ; 42(6): 892-899, 2019 Jun 01.

Article en En | MEDLINE | ID: mdl-30956264

Asunto(s)

Antineoplásicos/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Diterpenos/farmacología; Proteína HMGB1/antagonistas & inhibidores; Fenantrenos/farmacología; Animales; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Compuestos Epoxi/farmacología; Femenino; Proteína HMGB1/biosíntesis; Proteína HMGB1/genética; Proteína HMGB1/farmacología; Humanos; Células MCF-7; Ratones; Ratones Endogámicos BALB C; Terapia Molecular Dirigida; FN-kappa B/metabolismo; ARN Mensajero/antagonistas & inhibidores; ARN Mensajero/biosíntesis; ARN Mensajero/genética; Proteínas Recombinantes/farmacología; Transducción de Señal/efectos de los fármacos; Receptor Toll-Like 4/metabolismo; Ensayo de Tumor de Célula Madre; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

breast cancer; growth; high-mobility group box 1 (HMGB1); triptolide

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fenantrenos / Neoplasias de la Mama / Proteína HMGB1 / Diterpenos / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Biol Pharm Bull Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2019 Tipo del documento: Article

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