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Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties.
Partridge, Anthony W; Kaan, Hung Yi Kristal; Juang, Yu-Chi; Sadruddin, Ahmad; Lim, Shuhui; Brown, Christopher J; Ng, Simon; Thean, Dawn; Ferrer, Fernando; Johannes, Charles; Yuen, Tsz Ying; Kannan, Srinivasaraghavan; Aronica, Pietro; Tan, Yaw Sing; Pradhan, Mohan R; Verma, Chandra S; Hochman, Jerome; Chen, Shiying; Wan, Hui; Ha, Sookhee; Sherborne, Brad; Lane, David P; Sawyer, Tomi K.
Afiliación
  • Partridge AW; MSD International, 8 Biomedical Grove, #04-01/05 Neuros Building, Singapore 138665, Singapore. anthony_partridge@merck.com.
  • Kaan HYK; MSD International, 8 Biomedical Grove, #04-01/05 Neuros Building, Singapore 138665, Singapore. kristal.kaan@merck.com.
  • Juang YC; MSD International, 8 Biomedical Grove, #04-01/05 Neuros Building, Singapore 138665, Singapore. angela.juang@merck.com.
  • Sadruddin A; MSD International, 8 Biomedical Grove, #04-01/05 Neuros Building, Singapore 138665, Singapore. ahmad.sadruddin@merck.com.
  • Lim S; MSD International, 8 Biomedical Grove, #04-01/05 Neuros Building, Singapore 138665, Singapore. shuhui.lim@merck.com.
  • Brown CJ; p53Lab, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore 138648, Singapore. CJBrown@p53lab.a-star.edu.sg.
  • Ng S; p53Lab, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore 138648, Singapore. simon.ng@merck.com.
  • Thean D; p53Lab, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore 138648, Singapore. dthean@p53Lab.a-star.edu.sg.
  • Ferrer F; p53Lab, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore 138648, Singapore. fjferrer@p53Lab.a-star.edu.sg.
  • Johannes C; Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 8 Biomedical Grove, #07, Neuros Building, Singapore 138665, Singapore. charles_johannes@p53lab.a-star.edu.sg.
  • Yuen TY; Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 8 Biomedical Grove, #07, Neuros Building, Singapore 138665, Singapore. yuenty@ices.a-star.edu.sg.
  • Kannan S; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore. raghavk@bii.a-star.edu.sg.
  • Aronica P; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore. pietroa@bii.a-star.edu.sg.
  • Tan YS; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore. tanys@bii.a-star.edu.sg.
  • Pradhan MR; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore. mohanrp@bii.a-star.edu.sg.
  • Verma CS; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore. chandra@bii.a-star.edu.sg.
  • Hochman J; Merck & Co., Inc., West Point, PA 19486, USA. jerome_hochman@merck.com.
  • Chen S; Merck & Co., Inc., Kenilworth, NJ 07033, USA. shiying.chen@merck.com.
  • Wan H; Merck & Co., Inc., Kenilworth, NJ 07033, USA. hui.wan@merck.com.
  • Ha S; Merck & Co., Inc., Kenilworth, NJ 07033, USA. sookhee_ha@merck.com.
  • Sherborne B; Merck & Co., Inc., Kenilworth, NJ 07033, USA. tomi.sawyer@merck.com.
  • Lane DP; p53Lab, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-04/05 Neuros/Immunos, Singapore 138648, Singapore. dplane@p53Lab.a-star.edu.sg.
  • Sawyer TK; Merck & Co., Inc., Boston, MA 02115, USA. sawyerkrt@aol.com.
Molecules ; 24(12)2019 Jun 20.
Article en En | MEDLINE | ID: mdl-31226791
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Conformación Proteica / Péptidos de Penetración Celular / Aminoácidos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Singapur
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Conformación Proteica / Péptidos de Penetración Celular / Aminoácidos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Singapur