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Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference.
Cai, Chunhui; Cooper, Gregory F; Lu, Kevin N; Ma, Xiaojun; Xu, Shuping; Zhao, Zhenlong; Chen, Xueer; Xue, Yifan; Lee, Adrian V; Clark, Nathan; Chen, Vicky; Lu, Songjian; Chen, Lujia; Yu, Liyue; Hochheiser, Harry S; Jiang, Xia; Wang, Q Jane; Lu, Xinghua.
Afiliación
  • Cai C; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Cooper GF; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Lu KN; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Ma X; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Xu S; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Zhao Z; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Chen X; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Xue Y; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Lee AV; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Clark N; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Chen V; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Lu S; Department of Biomedical Informatics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Chen L; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Yu L; Center for Causal Discovery, Pittsburgh, PA, United States of America.
  • Hochheiser HS; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States of America.
  • Jiang X; Magee Women's Cancer Research Center, Pittsburgh, PA, United States of America.
  • Wang QJ; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
  • Lu X; Center for Causal Discovery, Pittsburgh, PA, United States of America.
PLoS Comput Biol ; 15(7): e1007088, 2019 07.
Article en En | MEDLINE | ID: mdl-31276486
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos