DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis.

Milani, Mateus; Beckett, Alison J; Al-Zebeeby, Aoula; Luo, Xu; Prior, Ian A; Cohen, Gerald M; Varadarajan, Shankar.

Afiliación

Milani M; 1Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.
Beckett AJ; 2Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.
Al-Zebeeby A; 1Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.
Luo X; 3Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198 USA.
Prior IA; 2Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.
Cohen GM; 1Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.
Varadarajan S; 4Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, Ashton Street, Liverpool, L69 3GE UK.

Cell Death Discov ; 5: 117, 2019.

Article en En | MEDLINE | ID: mdl-31341643