Subcortical lesions due to cobalamin deficiency: an unusual MRI lesion pattern.
Nutr Neurosci
; 24(7): 564-568, 2021 Jul.
Article
en En
| MEDLINE
| ID: mdl-31454297
ABSTRACT
We present a 44-year-old male patient with new onset of right focal epilepsy and bilateral hand hypesthesia. Cerebral MRI showed bilateral T2w/DWI hyperintense subcortical lesions in the cingulate gyrus, insula, and amygdala, whereas spinal MRI revealed a cervical posterior column lesion, corresponding to subacute combined degeneration. Laboratory workup revealed a cobalamin deficiency due to type A gastritis, and no evidence of antibodies associated with limbic encephalitis. After sufficient cobalamin substitution, the cerebral and spinal lesions gradually regressed. Our case represents a unique cerebral subcortical MRI lesion pattern in a patient with epilepsy and cobalamin deficiency. Thus, the latter represents an important differential diagnosis for autoimmune encephalitis.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Deficiencia de Vitamina B 12
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Corteza Insular
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Giro del Cíngulo
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Amígdala del Cerebelo
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Nutr Neurosci
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
NEUROLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Alemania