Carthamus tinctorius L. extract activates insulin-like growth factor-I receptor signaling to inhibit FAS-death receptor pathway and suppress lipopolysaccharides-induced H9c2 cardiomyoblast cell apoptosis.

Tung, Chun-Liang; Ju, Da-Tong; Velmurugan, Bharath Kumar; Ban, Bo; Dung, Tran D; Hsieh, Dennis J-Y; P Viswanadha, Vijaya; Day, Cecilia H; Lin, Yueh-Min; Huang, Chih-Yang

Tung, Chun-Liang; Ju, Da-Tong; Velmurugan, Bharath Kumar; Ban, Bo; Dung, Tran D; Hsieh, Dennis J-Y; P Viswanadha, Vijaya; Day, Cecilia H; Lin, Yueh-Min; Huang, Chih-Yang.

Afiliación

Tung CL; Department of Food Nutrition and Healthy Biotechnology, Asia University, Taichung, Taiwan.
Ju DT; Department of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan.
Velmurugan BK; Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Ban B; Institute of Research and Development, Duy Tan University, Da Nang, 550000, Vietnam.
Dung TD; Department of Biotechnology, Asia University, Taichung, Taiwan.
Hsieh DJ; Department of Endocrinology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, China.
P Viswanadha V; School of Chinese Medicine, Vietnam Academy of Traditional Medicine, Ha Noi, Vietnam.
Day CH; Clinical Laboratory, School of Medical Laboratory and Biotechnology, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung, Taiwan.
Lin YM; Department of Biotechnology, Bharathiar University, Coimbatore, India.
Huang CY; Department of Nursing, MeiHo University, Pingtung, Taiwan.

Environ Toxicol ; 34(12): 1320-1328, 2019 Dec.

Article en En | MEDLINE | ID: mdl-31486215

Asunto(s)

Apoptosis/efectos de los fármacos; Carthamus tinctorius/química; Extractos Vegetales/farmacología; Receptor IGF Tipo 1/metabolismo; Transducción de Señal/efectos de los fármacos; Receptor fas/metabolismo; Animales; Carthamus tinctorius/metabolismo; Caspasa 3/metabolismo; Línea Celular; Regulación de la Expresión Génica/efectos de los fármacos; Lipopolisacáridos/farmacología; Proteínas Mitocondriales/genética; Proteínas Mitocondriales/metabolismo; Miocitos Cardíacos/citología; Miocitos Cardíacos/efectos de los fármacos; Miocitos Cardíacos/metabolismo; Extractos Vegetales/química; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Ratas; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Carthamus tinctorius L; FADD; FAS; FAS-L; IGF-I; caspase

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Extractos Vegetales / Transducción de Señal / Receptor IGF Tipo 1 / Apoptosis / Receptor fas / Carthamus tinctorius Límite: Animals Idioma: En Revista: Environ Toxicol Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Taiwán

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