An adiponectin receptor agonist antibody stimulates glucose uptake and fatty-acid oxidation by activating AMP-activated protein kinase.

Jung, Dokyung; Bucher, Felicitas; Ryu, Suyeon; Jeong, Jongwon; Lee, Beom Yong; Jeong, Youngtae; Kim, Minseok S; Oh, Yong-Seok; Baek, Moon-Chang; Yoon, Jong Hyuk; Yea, Kyungmoo

Jung, Dokyung; Bucher, Felicitas; Ryu, Suyeon; Jeong, Jongwon; Lee, Beom Yong; Jeong, Youngtae; Kim, Minseok S; Oh, Yong-Seok; Baek, Moon-Chang; Yoon, Jong Hyuk; Yea, Kyungmoo.

Afiliación

Jung D; Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Bucher F; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Ryu S; Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Jeong J; Department of New Biology, DGIST, Daegu 42988, Republic of Korea.
Lee BY; Department of New Biology, DGIST, Daegu 42988, Republic of Korea.
Jeong Y; Department of New Biology, DGIST, Daegu 42988, Republic of Korea.
Kim MS; Department of New Biology, DGIST, Daegu 42988, Republic of Korea.
Oh YS; Department of Brain-Cognitive Science, DGIST, Daegu 42988, Republic of Korea.
Baek MC; Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Yoon JH; Department of Neural Development and Disease, Korea Brain Research Institute, Daegu 41068, Republic of Korea.
Yea K; Department of New Biology, DGIST, Daegu 42988, Republic of Korea. Electronic address: ykm31@dgist.ac.kr.

Cytokine ; 126: 154863, 2020 02.

Article en En | MEDLINE | ID: mdl-31629112

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Ácidos Grasos/metabolismo; Glucosa/metabolismo; Receptores de Adiponectina/agonistas; Receptores de Adiponectina/inmunología; Acetil-CoA Carboxilasa/metabolismo; Adiponectina/metabolismo; Animales; Glucemia/metabolismo; Línea Celular; Diabetes Mellitus Tipo 2/metabolismo; Técnicas de Silenciamiento del Gen; Glucosa/farmacología; Humanos; Metabolismo de los Lípidos; Masculino; Ratones; Ratones Endogámicos C57BL; Fibras Musculares Esqueléticas/metabolismo; Músculo Esquelético/metabolismo; FN-kappa B/metabolismo; Oxidación-Reducción; Fosforilación; ARN Interferente Pequeño; Receptores de Adiponectina/genética; Transducción de Señal/efectos de los fármacos; Transducción de Señal/genética

Palabras clave

AMPK; Adiponectin; Agonist antibody; Diabetes

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Adiponectina / Proteínas Quinasas Activadas por AMP / Ácidos Grasos / Glucosa Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cytokine Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article

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