Your browser doesn't support javascript.
loading
Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum.
Suthiphasilp, Virayu; Maneerat, Wisanu; Andersen, Raymond J; Phukhatmuen, Piyaporn; Pyne, Stephen G; Laphookhieo, Surat.
Afiliación
  • Andersen RJ; Department of Chemistry and Department of Earth, Ocean & Atmospheric Sciences , University of British Columbia , 2036 Main Mall , Vancouver , BC , Canada V6T 1Z1.
  • Pyne SG; School of Chemistry and Molecular Bioscience , University of Wollongong , Wollongong , New South Wales 2522 , Australia.
J Nat Prod ; 82(11): 3176-3180, 2019 11 22.
Article en En | MEDLINE | ID: mdl-31661271
Five new aristolactam alkaloids (1-5), dasymaschalolactams A-E, and the first isolation of dasymaschalolactone (17) as a natural product, together with 19 known compounds (6-16 and 18-25) were isolated from the twig extract of Dasymaschalon dasymaschalum. Their structures were elucidated by spectroscopic methods as well as comparisons made from the literature. Compounds 20 and 21 showed α-glucosidase inhibitory activities with IC50 values of 4.5 and 24.7 µM, respectively.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Annonaceae / Inhibidores Enzimáticos / Inhibidores de Glicósido Hidrolasas / Hipoglucemiantes / Lactamas Idioma: En Revista: J Nat Prod Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Annonaceae / Inhibidores Enzimáticos / Inhibidores de Glicósido Hidrolasas / Hipoglucemiantes / Lactamas Idioma: En Revista: J Nat Prod Año: 2019 Tipo del documento: Article