Regulation plays a multifaceted role in the retention of gene duplicates.
PLoS Biol
; 17(11): e3000519, 2019 11.
Article
en En
| MEDLINE
| ID: mdl-31756186
ABSTRACT
A gene duplication can lead to all sorts of problems in a cell. However, it can also lead to all sorts of benefits. Beneficial or not, the gene duplicates might be kept in the genome because of several different reasons. For instance, if natural selection works towards optimizing one function of a gene at the expense of another, then gene duplication could resolve this conflict by separating the functions in two genes. Here, we outline evolutionary incentives to keep a duplicated gene in the genome, focusing on divergence in expression and trade-off resolution as featured in a new and exciting paper published in this edition of PLOS Biology.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Evolución Molecular
/
Duplicación de Gen
Idioma:
En
Revista:
PLoS Biol
Asunto de la revista:
BIOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Canadá