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Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
Wyatt, Ryan M; Fraser, Ian; Welty, Natalie; Lord, Brian; Wennerholm, Michelle; Sutton, Steven; Ameriks, Michael K; Dugovic, Christine; Yun, Sujin; White, Allison; Nguyen, Leslie; Koudriakova, Tatiana; Tian, Gaochao; Suarez, Javier; Szewczuk, Lawrence; Bonnette, William; Ahn, Kay; Ghosh, Brahma; Flores, Christopher M; Connolly, Peter J; Zhu, Bin; Macielag, Mark J; Brandt, Michael R; Chevalier, Kristen; Zhang, Sui-Po; Lovenberg, Timothy; Bonaventure, Pascal.
Afiliación
  • Wyatt RM; Janssen Research & Development, LLC, San Diego, California rwyatt2@its.jnj.com.
  • Fraser I; Janssen Research & Development, LLC, San Diego, California.
  • Welty N; Janssen Research & Development, LLC, San Diego, California.
  • Lord B; Janssen Research & Development, LLC, San Diego, California.
  • Wennerholm M; Janssen Research & Development, LLC, San Diego, California.
  • Sutton S; Janssen Research & Development, LLC, San Diego, California.
  • Ameriks MK; Janssen Research & Development, LLC, San Diego, California.
  • Dugovic C; Janssen Research & Development, LLC, San Diego, California.
  • Yun S; Janssen Research & Development, LLC, San Diego, California.
  • White A; Janssen Research & Development, LLC, San Diego, California.
  • Nguyen L; Janssen Research & Development, LLC, San Diego, California.
  • Koudriakova T; Janssen Research & Development, LLC, San Diego, California.
  • Tian G; Janssen Research & Development, LLC, San Diego, California.
  • Suarez J; Janssen Research & Development, LLC, San Diego, California.
  • Szewczuk L; Janssen Research & Development, LLC, San Diego, California.
  • Bonnette W; Janssen Research & Development, LLC, San Diego, California.
  • Ahn K; Janssen Research & Development, LLC, San Diego, California.
  • Ghosh B; Janssen Research & Development, LLC, San Diego, California.
  • Flores CM; Janssen Research & Development, LLC, San Diego, California.
  • Connolly PJ; Janssen Research & Development, LLC, San Diego, California.
  • Zhu B; Janssen Research & Development, LLC, San Diego, California.
  • Macielag MJ; Janssen Research & Development, LLC, San Diego, California.
  • Brandt MR; Janssen Research & Development, LLC, San Diego, California.
  • Chevalier K; Janssen Research & Development, LLC, San Diego, California.
  • Zhang SP; Janssen Research & Development, LLC, San Diego, California.
  • Lovenberg T; Janssen Research & Development, LLC, San Diego, California.
  • Bonaventure P; Janssen Research & Development, LLC, San Diego, California.
J Pharmacol Exp Ther ; 372(3): 339-353, 2020 03.
Article en En | MEDLINE | ID: mdl-31818916
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Encéfalo / Leucocitos Mononucleares / Inhibidores Enzimáticos / Monoacilglicerol Lipasas Límite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Exp Ther Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Encéfalo / Leucocitos Mononucleares / Inhibidores Enzimáticos / Monoacilglicerol Lipasas Límite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Exp Ther Año: 2020 Tipo del documento: Article