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Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.
Doebele, Robert C; Drilon, Alexander; Paz-Ares, Luis; Siena, Salvatore; Shaw, Alice T; Farago, Anna F; Blakely, Collin M; Seto, Takashi; Cho, Byung Chul; Tosi, Diego; Besse, Benjamin; Chawla, Sant P; Bazhenova, Lyudmila; Krauss, John C; Chae, Young Kwang; Barve, Minal; Garrido-Laguna, Ignacio; Liu, Stephen V; Conkling, Paul; John, Thomas; Fakih, Marwan; Sigal, Darren; Loong, Herbert H; Buchschacher, Gary L; Garrido, Pilar; Nieva, Jorge; Steuer, Conor; Overbeck, Tobias R; Bowles, Daniel W; Fox, Elizabeth; Riehl, Todd; Chow-Maneval, Edna; Simmons, Brian; Cui, Na; Johnson, Ann; Eng, Susan; Wilson, Timothy R; Demetri, George D.
Afiliación
  • Doebele RC; Division of Medical Oncology, University of Colorado, Aurora, CO, USA.
  • Drilon A; Weill Cornell Medical College, New York, NY, USA; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Paz-Ares L; Hospital Universitario 12 de Octubre, H120H120-CNIO Lung Cancer Clinical Research Unit, Universidad Complutense & Ciberonc, Madrid, Spain.
  • Siena S; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
  • Shaw AT; Department of Oncology and Medical Radiotherapy, Massachusetts General Hospital, Boston, MA, USA.
  • Farago AF; Department of Oncology and Medical Radiotherapy, Massachusetts General Hospital, Boston, MA, USA.
  • Blakely CM; Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
  • Seto T; National Kyushu Cancer Center, Fukuoka, Japan.
  • Cho BC; Yonsei Cancer Center, Seoul, South Korea.
  • Tosi D; Institut Régional Du Cancer de Montpellier, Montpellier, France.
  • Besse B; Gustave Roussy Cancer Campus, Villejuif Cedex, Paris, France.
  • Chawla SP; Sarcoma Oncology Center, Santa Monica, CA, USA.
  • Bazhenova L; University of California San Diego, Moores Cancer Center, La Jolla, CA, USA.
  • Krauss JC; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Chae YK; Department of Medicine, Northwestern University, Chicago, IL, USA.
  • Barve M; Mary Crowley Cancer Center, Dallas, TX, USA.
  • Garrido-Laguna I; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Liu SV; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
  • Conkling P; US Oncology Research, Virginia Oncology Associates, Norfolk, VA, USA.
  • John T; Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, VIC, Australia.
  • Fakih M; City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Sigal D; Scripps Clinic and Scripps MD Anderson Cancer Center, La Jolla, CA, USA.
  • Loong HH; The Chinese University of Hong Kong, Sha Tin, Hong Kong.
  • Buchschacher GL; Southern California Permanente Medical Group, Los Angeles, CA, USA.
  • Garrido P; Department of Medical Oncology, Universidad de Alcalá and Ciberonc, Madrid, Spain; Ramón y Cajal Health Research Institute, Madrid, Spain; Medical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
  • Nieva J; Norris Cancer Center, University of Southern California, Los Angeles, CA, USA.
  • Steuer C; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
  • Overbeck TR; Department of Hematology and Oncology, University of Göttingen, Göttingen, Germany.
  • Bowles DW; School of Medicine, University of Colorado, Aurora, CO, USA.
  • Fox E; Department of Developmental Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Riehl T; Genentech, South San Francisco, CA, USA.
  • Chow-Maneval E; Ignyta, San Diego, CA, USA.
  • Simmons B; Genentech, South San Francisco, CA, USA.
  • Cui N; Genentech, South San Francisco, CA, USA.
  • Johnson A; Ignyta, San Diego, CA, USA.
  • Eng S; Genentech, South San Francisco, CA, USA.
  • Wilson TR; Genentech, South San Francisco, CA, USA.
  • Demetri GD; Dana-Farber Cancer Institute and Ludwig Center, Harvard Medical School, Boston, MA, USA. Electronic address: gdemetri@dfci.harvard.edu.
Lancet Oncol ; 21(2): 271-282, 2020 02.
Article en En | MEDLINE | ID: mdl-31838007
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzamidas / Biomarcadores de Tumor / Receptores de Factor de Crecimiento Nervioso / Inhibidores de Proteínas Quinasas / Fusión Génica / Indazoles / Neoplasias / Antineoplásicos Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzamidas / Biomarcadores de Tumor / Receptores de Factor de Crecimiento Nervioso / Inhibidores de Proteínas Quinasas / Fusión Génica / Indazoles / Neoplasias / Antineoplásicos Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos