Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-&#954;B/IL-6/STAT3 Signaling Pathway.

Wu, Jia-Sheng; Liu, Qian; Fang, Shan-Hua; Liu, Xing; Zheng, Min; Wang, Tian-Ming; Zhang, Hua; Liu, Ping; Zhou, Hu; Ma, Yue-Ming

Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-κB/IL-6/STAT3 Signaling Pathway.

Wu, Jia-Sheng; Liu, Qian; Fang, Shan-Hua; Liu, Xing; Zheng, Min; Wang, Tian-Ming; Zhang, Hua; Liu, Ping; Zhou, Hu; Ma, Yue-Ming.

Afiliación

Liu Q; Department of Analytical Chemistry and CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 555 Zuchongzhi Road , Shanghai 201203 , China.
Fang SH; University of Chinese Academy of Sciences , Number 19A Yuquan Road , Beijing 100049 , China.
Liu X; Department of Analytical Chemistry and CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 555 Zuchongzhi Road , Shanghai 201203 , China.
Zheng M; Department of Analytical Chemistry and CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 555 Zuchongzhi Road , Shanghai 201203 , China.
Liu P; Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases , Shuguang Hospital , Shanghai 201203 , China.
Zhou H; Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases , Shuguang Hospital , Shanghai 201203 , China.
Ma YM; Department of Analytical Chemistry and CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 555 Zuchongzhi Road , Shanghai 201203 , China.

J Proteome Res ; 19(2): 677-687, 2020 02 07.

Article en En | MEDLINE | ID: mdl-31852184

Asunto(s)

Interleucina-6; FN-kappa B; Medicamentos Herbarios Chinos; Interleucina-6/genética; Hígado/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Proteómica; Transducción de Señal

Palabras clave

Huangqi decoction; IL-6; NF-κB; STAT3; intrahepatic cholestasis; proteomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Interleucina-6 Idioma: En Revista: J Proteome Res Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article

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