Five-year follow-up of patients treated with intra-dermal botulinum toxin for axillary hyperhidrosis.
Ir J Med Sci
; 189(3): 1023-1026, 2020 Aug.
Article
en En
| MEDLINE
| ID: mdl-31898163
ABSTRACT
BACKGROUND:
Axillary hyperhidrosis is a common complaint affecting 5% of the general population. It can significantly impact quality of life (QOL) and may be extremely debilitating. Administration of intra-dermal botulinum toxin type-A (Botox) has been proven to be effective in managing axillary hyperhidrosis; however, to date, no long-term data has assessed its efficacy.AIM:
We aim to assess long-term (> 5 years) QOL outcomes in this patient cohort.METHODS:
In this single-centre series, all patients attending for axillary botox, with five or more years of follow-up, were prospectively included. QOL was assessed in all patients using the validated assessment tool, the modified Dermatology Life Quality Index (DLQI). Standard statistical methods were utilised with data reported as mean (± standard deviation). Subgroup analysis utilising previously published departmental data allowed for further assessment of change in QOL over time.RESULTS:
A total of 75 patients (83% female) met the inclusion criteria with 67% completing the DLQI assessment. Follow-up ranged from 5 to 10 years with a mean age of 37.6 years (± 8.82). The mean number of treatments over the study period was 12 (± 3.1). Mean overall post-treatment DLQI score was 1.6 (± 2.01). This represented a significant improvement in patient QOL (p = < 0.0001) associated with long-term botox application. This statistical significance was identified consistently across all components of the DLQI tool.CONCLUSION:
These data suggest that the established early QOL benefits associated with intra-dermal botox administration for AH are sustained in the long term. This benefit was seen across all subsets of the DLQI tool.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Axila
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Toxinas Botulínicas Tipo A
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Hiperhidrosis
Tipo de estudio:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Ir J Med Sci
Año:
2020
Tipo del documento:
Article
País de afiliación:
Irlanda