Your browser doesn't support javascript.
loading
NiH-Catalyzed Migratory Defluorinative Olefin Cross-Coupling: Trifluoromethyl-Substituted Alkenes as Acceptor Olefins to Form gem-Difluoroalkenes.
Chen, Fenglin; Xu, Xianfeng; He, Yuli; Huang, Genping; Zhu, Shaolin.
Afiliación
  • Chen F; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Material, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
  • Xu X; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Material, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
  • He Y; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Material, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
  • Huang G; Department of Chemistry, School of Science, Tianjin University, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072, China.
  • Zhu S; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Material, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
Angew Chem Int Ed Engl ; 59(13): 5398-5402, 2020 03 23.
Article en En | MEDLINE | ID: mdl-31951070
ABSTRACT
We report a NiH-catalyzed migratory defluorinative coupling between two electronically differentiated olefins. A broad range of unactivated donor olefins can be joined directly to acceptor olefins containing an electron-deficient trifluoromethyl substituent in both intra- and intermolecular fashion to form gem-difluoroalkenes. This migratory coupling shows both site- and chemoselectivity under mild conditions, with the formation of a tertiary or quaternary carbon center.
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: China