[Advances in proteomic studies of post-translational modifications during spermatogenesis].
Sheng Li Xue Bao
; 72(1): 75-83, 2020 Feb 25.
Article
en Zh
| MEDLINE
| ID: mdl-32099985
ABSTRACT
Spermatogenesis is composed of a series of complex biological events, which are regulated by complex factors. There is a phenomenon of delayed translation in spermatogenesis, so the changes of transcription and protein expression are not completely consistent. Thus post-translational modifications (PTMs) play a key role in spermatogenic biological events. In recent years, the development of proteomics has deepened the discovery of PTM. This paper reviews the advances in multiple PTMs proteomic during testicular spermatogenesis. Their effects on sperm function and fertility, as well as their significance for future diagnosis and treatment are discussed.
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Banco de datos:
MEDLINE
Asunto principal:
Espermatogénesis
/
Espermatozoides
/
Procesamiento Proteico-Postraduccional
/
Proteómica
Límite:
Animals
/
Humans
/
Male
Idioma:
Zh
Revista:
Sheng Li Xue Bao
Año:
2020
Tipo del documento:
Article
País de afiliación:
China