How an unusual chemosensory system forms arrays on the bacterial nucleoid.
Biochem Soc Trans
; 48(2): 347-356, 2020 04 29.
Article
en En
| MEDLINE
| ID: mdl-32129822
ABSTRACT
Chemosensory systems are signaling pathways elegantly organized in hexagonal arrays that confer unique functional features to these systems such as signal amplification. Chemosensory arrays adopt different subcellular localizations from one bacterial species to another, yet keeping their supramolecular organization unmodified. In the gliding bacterium Myxococcus xanthus, a cytoplasmic chemosensory system, Frz, forms multiple clusters on the nucleoid through the direct binding of the FrzCD receptor to DNA. A small CheW-like protein, FrzB, might be responsible for the formation of multiple (instead of just one) Frz arrays. In this review, we summarize what is known on Frz array formation on the bacterial chromosome and discuss hypotheses on how FrzB might contribute to the nucleation of multiple clusters. Finally, we will propose some possible biological explanations for this type of localization pattern.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Quimiotaxis
/
Myxococcus xanthus
/
Citoplasma
Idioma:
En
Revista:
Biochem Soc Trans
Año:
2020
Tipo del documento:
Article
País de afiliación:
Francia